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Dissertation for Ph.D. Ph.D. Persian Summary Aripiprazole is an atypical antipsychotic drug that shows its therapeutic effect with a combination of antagonistic activity of 5-HT2A receptor and partial agonistic activity of 5-HT1A and D2 dopamine receptors. This drug is used in the treatment of schizophrenia, type I bipolar disorders and as an adjunctive treatment in major ...