Preparation of cream containing snail extract and ostrich oil and checking its physical and chemical properties

Dissertation for obtaining a master's degree ((M.Sc))

Inclination: Applied Chemistry

Persian summary

The purpose of this research is to investigate the common fatty acids of ostrich oil and to determine the amount of retinol in snail secretion to make a cream with therapeutic properties.

Since 3000 years ago, the therapeutic properties of ostrich oil have been used to treat wounds, burns, joint pain and skin disorders. Eczema and similar cases are known.

Since ancient times, snail secretion has been used in medicine to treat pain related to sunburn, wounds and as a skin softener.

Some of the properties of ostrich oil are as follows: The ionic number was 70.64 and the soap number was 184, and free fatty acids such as oleic acid were 0.21.

The fatty acids of the oil were separated by wet melt extraction, and were identified and separated by GC MASS device. This study shows that ostrich oil has anti-inflammatory and pain-relieving properties due to its short-chain fatty acids that easily pass through the skin and can be used in medicinal, cosmetic, health and food applications. In the continuation of this research, 9 cream formulations were prepared from the obtained oil, and the physicochemical analyzes of 4 of them were found to be appropriate.

To prepare snails, for this purpose, after extracting vitamin A present in snail secretion, the amount was determined. Then, 9 cream formulations were prepared from the obtained extract, and the physicochemical analyzes of 4 of them were evaluated as suitable.

Ostrich oil, snail secretion, fatty acids, GC/MASS, vitamin A, cream

Introduction

The use of cosmetics and health products has a history as far back as human history. The available findings from the petroglyphs and the history of this land, show the attention and care of the people of Iran to health and its role in maintaining health. The teachings of the Mobin religion of Islam have always been based on the observance of health, cleanliness, and the dressing and adornment of Muslims.

The design and manufacture of cosmetics and hygiene products, like other products today, are based on scientific principles. The range of products has caused a lot of research to be done in this direction and to try to reach the consumers with healthy products without any problems. Numerous scientific articles and books that have been published in the field of knowledge of the above products are proof of this claim.

J Production and Trading Company, the first producer of skin softening and anti-crack cream, has remained a familiar name with more than half a century of brilliant history in the public mind and continues to strive to ensure the health and safety of society.

This collection In line with the world's modern technology in specialized laboratories, with the efforts of expert and experienced staff and the use of fully automatic machines, in line with the development and improvement of product quality and increasing customer satisfaction, compliance with legal requirements, the establishment of the ISO90012008 quality management system has been prioritized in its quality activities.

Chapter One

Overview

1-1. The necessity of the importance of the subject

Today, urban life and distance from nature has caused various diseases in humans, since this way of life seems inevitable today, the proposed solutions are the use of chemical and industrial drugs according to the available facilities. They also have their advantages and disadvantages. The experience of several thousand years of human life on the planet has taught him that the use of natural substances has more advantages and fewer disadvantages and more effective medicinal effects. In this regard, the production and use of products that replace chemical drugs such as vegetable and animal extracts and vegetable and animal oils are suggested.

1-2. Statement of the problem

In ancient times, snails were used in medicine due to their softening properties and the treatment of sunburn. Snails can regenerate their damaged skin cells in less than 48 hours with the slimy substance they produce when they are injured. Based on this, in the present study, we decided to extract the retinol present in snail secretion and determine its amount in order to make a cream for the treatment of wrinkles. This oil is obtained from 3 birds of the ratite family, meaning broad-breasted, including ostrich, rhea, and amu. Its continuous consumption helps to maintain the health of the skin, muscles and bones. Accordingly, in this present study, we decided to seek profit after extracting and identifying the components of fatty acids and separating them in order to make a cream for the treatment of skin wrinkles. (6)

1-3. Objectives

With the increasing expansion of the ostrich breeding industry in Iran, which began seriously with the arrival of 5000 chickens in 1378, and the purpose of implementing this plan was to use the meat of this bird in the first place and other products such as feathers and skin, and the fat of this bird was thrown away as waste, it seemed that the available fat would be a suitable source for the production of cosmetic, health and therapeutic products. (10)

According to the number of ostrich breeding farms in the country and significant amounts of fat produced for which no specific use has been defined at the moment, and considering the properties of this valuable material that has been used by mankind for about 3000 years in various cosmetic, health and therapeutic matters. Although snail cream and ostrich oil cream are sold in the Iranian market, they are not domestically produced. In this research, an attempt is made to produce a native sample of this cream with higher efficiency, that's why we felt the need to implement this project in order to free the country from the trap of dependence and become self-sufficient in this sector as well as in other sectors.

Chapter Two

Review of past texts

2-1. General information about the skin

Our skin is the first point of contact with the world around us and with its important functions, it plays a role much more than a simple covering for the body. After the skeletal muscles, it is the heaviest (50% of the total body weight) and after the lungs (including their alveolar surface), it is the largest (2000 cm2) organ of the living body.

The thickness of the skin is very variable and depends on various factors such as age, sex, individual fluctuations, heredity, occupation, race and so on. It varies, but on average it fluctuates between 4-0.7 mm.

In terms of hair coverage, the skin can be divided into two types: 1) Naked or Glabrous, which is visible only on the palms and feet, and 2) Hairy, which covers the entire body and varies in terms of the number and thickness of the hair follicles that cover it. It is extensive. (3)

Skin pH is acidic and often in the range of 2.4-6.5. This is caused by the presence of sebum fatty acids, the presence of amino acids in the hydrolipidic layer, and the presence of lactic acid, ascorbic acid, and citric acid. It is in this layer, it makes the conditions unfavorable for the growth of bacteria.

Skin color depends on many factors including race, occupation, age, weather conditions and so on. is dependent Two types of melanin found in the epidermis, Eumelanin with brown-black color and Fumelanim with red-yellow color, which are made by melanocytes, not only determine the color of people's skin, but are the natural covering of the body against sunlight.

2-1-1. Anatomical structure of the skin

Detailed examination of the skin shows the presence of 3 distinct structural layers. The outermost layers, which are the main focus in cosmetic and health purposes, are called epidermis.